Education and Trainings
1978-1988 Primary/Secondary/High School #164 Yerevan, Armenia Graduated with distinction (Gold Excellency medal)
1988-1994 Medical Student Yerevan State Medical University Yerevan, Armenia
Faculty of Internal Medicine Graduated with Distinction; Diploma of General Practitioner
1994-1997 Clinical Resident Yerevan State Medical University Yerevan, Armenia
Department of Neurology and Neurological Surgery, 1998 Advanced Teaching and Psychology Course Yerevan State Medical University
Yerevan, Armenia Faculty of Improvement of Professional Skills of Teaching Staff Certificate of Teacher and Psychologist
1997-2001 PhD Fellowship Yerevan State Medical University
Department of Neurology and Neurological Surgery
2001 PhD Thesis “Cerebral Blood Flow Infringements in Traumatic Brain Injury”
2001 Salzburg Cornell Neurology Seminars Salzburg, Austria
2003 Salzburg Cornell Neurosurgical Seminars Salzburg, Austria
2004-2005 Fulbright Fellowship Noble Lab, Department of Neurological Surgery,
UCSF, San Francisco, CA, the United States 2006 Neurology Internship
Department of Neurology, AKH, Vienna, Austria
2007 Second PhD Thesis (DSci) “The role of regional immune, morphological and
metabolic shifts in pathogenesis of experimental cortical injury”
2008 Alzheimer Disease International University trainings
ADI, London, United Kingdom
2009 EFNS Neurology Teaching Course,
Yerevan, Armenia
2011 Neuropelveology Training, Hirslanden Klinik, Zurich, Switzerland
2012 Good ClinicalPractice Trainings, London, UK, Yerevan, Armenia
2013 SpeakersAcademy, Singapour
Professional Experience
1992-1993 Medical Attendant
International Post-Trauma Rehabilitation Center, Yerevan, Armenia
1994-2004 Neurologist /Neurological Surgeon
Neurosurgery Department
“Armenia” Republic Medical Center, Yerevan, Armenia
Main Duties:
Organization and performing of the diagnostics and treatment of patients with various pathologies (both neurological and neurosurgical) of the Central and Peripheral Nervous System
Surgical treatment of the Severe Head Injury, Spinal Chord Injuries, Central Nervous System tumors, cerebro-vascular pathology etc, and further rehabilitation. Non surgical – Investigation and treatment of patients with Neurological pathology: stroke, TIA, degenerative disorders of CNS, complicated ostheochondrosis, spinal cord diseases
Regular doctor practice with hospital duties, night shifts, emergency medical service duties, patients consulting etc.
1997-2006 Assistant Professor
Neurology and Neurosurgery Chair
Yerevan State Medical University, Yerevan, Armenia
Main Activity:
Lectures for 4th year medical students on Traumatic Brain Injury, Spinal Cord Injury, Central Nervous System Tumors and Modern Diagnostics in Neurology and Neurological Surgery, 200 hours per semester
Practical course for 4th year medical students on neurological surgery, seminars on Modern Diagnostics (Ultrasound, CT and MRI), Back Pain, Spinal Cord Injury, annually 400 hours
Research in Cerebral Hemodynamics, in Cerebral Blood Flow infringement in Traumatic Brain Injury, Cerebral Vascular Diseases, Stroke, using of the TranscranialDopplerography, correlation betweenneuroimaging (CT, MRI) data and quantitative investigations, Rehabilitation of Neurological and Neurosurgical patients
Special interest in Neuroscience, Brain Injury research, Cerebral Blood Flow research, Neuroimaging, Neurosonology, Neuroradiology
2004-2005 Visiting Postdoc
Noble Lab, Department of Neurosurgery, UCSF
521 Parnassus, C-224, San Francisco, CA 94143 – 0520, USA
Phone: (415) 502-2667Fax: (415) 476-5634
Basic Neuroscience,Traumatic Brain InjuryResearch
Main Activity:
Animal (small rodent) surgeries and cortical injury,stereotaxic injections,animal postsurgical care
Animal genotyping, PCR reactions
In vivo MRI imaging and analysis
Animal Euthanasia, Perfusion, Brain dissection
Cerebral Blood Flow investigations using Laser Doppler device
Histo- and Immunohistochemicalstainings of the brain tissues (TUNEL, NADPHd, CD4, CD8, CD45, GR-1, Pearl’s reaction,Lectin etc), CNS histology and further investigation with microscopy and cell counting, imaging (including immuno fluorescence), statistical analysis with Prism applications.
2006 Research Neuroscientist andPrincipal Investigator
Scentific Research Center,Yerevan State Medical University
Research in Neuroscience: General Pathology, Apoptosis, Cerebral Blood Flow in different neurological disorders, neuromorphology: microglia/macrophages, immune inflammation of the brain.
Establishing of committee and institutional protocols for human subjects and animal in research.
Foundation of Scientific and Research Facilities in Medical University, Cell/Tissue Culture Labs.
Creation of scientific basis and facilities for the biomedical research and neuroscience in Armenia.
2007, AprilAssociated Professor of Neurology,
Department of Neurology, Yerevan State Medical University
2007, MayExecutive Secretary
2009, May Vice Editor
“The New Armenian Medical Journal”Medical Scientific Magazine, Armenia
Article selection and peer review
Translations and publications
Implementation of new standards and demands of GLP and GCP in any of medical writings and presentations in Armenia
2007, October
-PresentProfessor and Chairman,
Departmentof Neurology, Yerevan State Medical University
New Curriculum Education of the clinical subject of Neurology for medical students (4th year of education)
New Curriculum Education of the clinical subject of Neurology for residents and family doctors (three year and one month long, respectively)
Clinical management of patient investigation and treatment during routine weekly rounds, clinical conferences, etc
Creations of evaluation and treatment protocols, on evidence based medicine basis, and good clinical practice regulations
2011-present Chairman, of Therapeutic Council, YSMU
University/Volonteer Services
2006 – present PhD Approval Committee, Yerevan State Medical University, Board member
2006 – present Fulbright Commission in Armenia, US Embassy to Yerevan, Board member
2006 – 2011 Bioethics Committee, Yerevan State Medical University, Board member
2007- present Yerevan State Medical University Scientific Council, Board member
2010 Co-Chairmen of First International Young Scientist Congress, Yerevan, Armenia
Other Skills
Languages: Armenian (native, fluent), English (fluent), Russian (fluent)
Computer skills: Office Applications (Microsoft Office, including word processing, spreadsheets, design), Microsoft Windows, Windows XP,Excels, PowerPoint presentations, Adobe Photoshop and InDesign applications, GraphPad Prism statistical applications, Internet /E-mail applications
Professional Awards
1997-98 Man of the Year, Cambridge Biographical Center, England, UK
1998 List of Outstanding Peoples of XX Century, Cambridge Biographical Center, England, UK, Member
2005 Abstract/ Poster Competition Award Winner (The 23rd National Neurotrauma
Symposium, USA)
2007 Best Presentation Award Winner (Yerevan State Medical University Scientific Session).
Association membership
1996-2004 Member of Armenian Neurosurgical Association, Secretary General 2001-2004
1999 International Brain Research Organization (IBRO), Armenian Branch Member
2003 Healthy Future, Medical Charitable Organization, Board Member
2005 National Neurotrauma Association (USA), Member
2006 Medical Chamber of Armenia, Secretary General starting 2009
2007 Armenian Neurology Association, Vice President starting 2009
2008 Armenian Alzheimer Association, President starting 2012
2009 Armenian National Multiple Sclerosis Society, President
Grants and Collaborations
2001 Open Society Institute Grant supported participation to Cornell-Salzburg Seminars on
Neurology, Salzburg, Austria
2002 CRDF travel grant to International Neurotrauma Symposium, Tampa, FL, USA
2003 Open Society Institute Grant supported participation to Cornell-Salzburg Seminars on
Neurological Surgery, Salzburg, Austria
2004 INTAS and INRO supported participation to Safety 2004 Conference, Vienna, Austria
2004-2005 Fulbright Fellowship Grant at UCSF, San Francisco, Ca, USA
2005 National Neurotrauma Symposium travel grant to 23rd Symposium at Washington, DC
2006 Austrian American Foundation, OMI sponsored Internship in Neurology at AKH,
Vienna, Austria
2006 INTAS travel grant to Regional Workshop INTAS – Sounth Caucasus, Tbilisi, Georgia
2006 IBRO-CEERC travel grant to the 2nd International Conference of the National Neuro-
Science Society of Romania, Romania
2008 Dementia in Armenia: Hidden Problem, Funding Research Grant from the National
Science Committee, under the Government of Republic of Armenia
2008 Alzheimer International travel/ accommodation grant to Alzheimer International
University, London, UK
2011-2013 MS in Armenia: Epidemiology, Gaps and Effective Management,Funding Research Grant from the National Science Committee, under the Government of Republic of Armenia
2012-2013 ELEVATE study of Neuropathic Pain, International Multicentral Clinical Study, AstellasPharma
Presentations at Conferences, Congress, Seminars
1995 IBRO Armenian Branch First ConferenceYerevan, Armenia
“Differential Treatment of IntracerebralHematomas of Various Ethiology”,Poster
1996 IBRO Armenian Branch Second ConferenceYerevan, Armenia
“Cerebral Hemodynamic Phases Following Severe Head Trauma:Hypoperfusion, Hyperemia and Vasospasm”,Poster
1997 Fifth IBRO World Congress of NeuroscienceJerusalem , Israel
“Peculiarities of Cerebral Collateral Blood Circulation in Brain Ischemia”,Poster
1998 International Stroke Society, Neurosonology Regional MeetingTbilisi, Georgia
“Quantitative Evaluation of Cerebral Blood Flow in Patients with Severe Head Injury“
Oral Presentation
1999 Yerevan State Medical University 70th Anniversary Scientific Conference Armenia
“Monitoring of Cerebral Hemodynamics Disturbances in Traumatic Brain Injury”,
Oral Presentation
2000 IBRO Armenian Branch Third ConferenceYerevan, Armenia
“Evaluation of Cerebral Blood Flow in Patients with Severe Head Injury“
Oral Presentation
2000 Armenian Anaesthesiological Second ConferenceYerevan, Armenia
“Application of TranscranialDopplerography in Acute Stroke“, Oral Presentation
2001 Salzburg-Cornell Neurology SeminarsSalzburg, Austria
“Neurosurgical Aspects of Dementia Treatment”, Oral Presentation
2001 12h World Congress of NeurosurgerySydney, Australia
“Cerebral Blood Flow in Traumatic Brain Injury”, Poster
2001 12h World Congress of NeurosurgerySydney, Australia
“Some aspects of neurosurgical treatment of Dementia”,Poster
2002 1st Joint Symposium of National and International Neurotrauma Societies,Tampa FL, “Primary and Delayed Ischemia in Severe Traumatic Brain Injury”, Poster
2003 Salzburg-Cornell Neurological Surgery SeminarsSalzburg, Austria
“Some surgical aspects in treatmentof Normotensive Hydrocephalus Dementia”
Oral Presentation
2003 2nd International Congress of Young Medics, Yerevan, Armenia
“The Understanding of the Problem of Brain Death”, Oral Presentation
2003 1stPan ArmenianInternational Surgical Congress, Yerevan, Armenia
“Cerebral Vasospasm after Subarachnoid Haemorrhage: Clinical Implications”
Oral Presentation
2005 Northern California Neurotrauma Spring Meeting, Sacramento, CA, USA
“Regional Cerebral Blood Flow and Apoptosis:Immature vs. Adult TBI”
Oral Presentation
2005 UCLA Neurotrauma Annual Meeting, Ojai, CA, USA
“Age-Dependent Prolonged GR-1PositiveLeukocyte Infiltration in the Injured Cortex”
Oral Presentation
2005 23rd National Neurotrauma Symposium, Washington DC, USA
“Age-dependent Temporal pattern of Cell Injury after TBI: Relation to Blood Flow, and
Activated Microglia/Macrophages”Poster and Oral Presentations
2005 23rd National Neurotrauma Symposium, Washington DC, USA
“Heme-Oxigenase-2 (HO-2) modulates Early Pathogenesis and Motor Recovery after Traumatic Brain Injury (TBI) to the Immature Brain” Poster Presentation
2005 23rd National Neurotrauma Symposium, Washington DC, USA
“Prolonged GR-1 Positive, Leukocyte Infiltration in the Injured Cortex is Age-Dependent
and Corresponds to Lesion Volume Expansion”Poster Presentation
2006 Regional Workshop INTAS – Sounth Caucasus 2006, Tbilisi, Georgia
“Possible cooperation in Neurotrauma Research between NIS and INTAS countries” Oral Presentation
2006 2nd International Conference of National Neuroscience Society of Romania, Bucharest,
Romania, “Temporal patterns of Irreversibly Injured Cells, Activated Microglia/
Macrophages and Cerebral Blood Flow in Neurotrauma”Oral Presentation
2006 1st Laboratory Diagnostics Delta Conference, Yerevan, Armenia
“Laboratory detection of Apoptosis by the TUNEL (TdT-FragEL* DNA Fragmentation
detection) imuno-hystochemical method”Oral Presentation
2007 YSMU Scientific Conference, “Efficacy of FlourescentLectin Studies in the Brain
Research” Oral Presentation, Yerevan, Armenia,Award for Best Presentation
2007 Bunatian Memorial International Neuroscience Symposium, “Unveiling brain
innate immune system: the role of microglia” Yerevan, Armenia, Oral Presentation
2008 Actual Problems of Dementia in Post-soviet Countries Conference, “Efficacy of alpha-
blockers in treatment of vascular dementia”, Moscow, Russia, Oral Presentation
2008 EFNS 12th Congress, “Multiple Sclerosis in Armenia: Threatening Growth rates”,
Madrid, Spain, Poster Presentation
2008 EFNS 12th Congress, “Dementia in Armenia: Alzheimer vs. Vascular”, Madrid, Spain,
Poster Presentation
2008 2nd International Forumof Neurologists“MS in Armenia”, oral presentation, Yerevan, Armenia
2009 UEMS Congress “The Role of Non Governmental Organizations – Medical Chamber – in Effective Reforming of the Public Health Sector and Medical Education”oral presentation, Brussel, Belgium
2009 Dementia in the Middle East 5th Regional Conference “Alzheimer Disease and Related Dementia in Armenia”, oral presentation, Limassol, Cyprus
2009 First Armenian Congress of Sexologists “Sexual Disorders in Neurological Patients: Initial Signs and Consequences”oral presentation, Yerevan, Armenia
2009 The Men’s Health First Armenian-Russian Congress “Urological Masks of Hidden Depression in Men”, Yerevan, Armenia
2010 Seventh Neuropathic Pain Congress of Turkey, Antalya, Turkey
2010 First International Congress of Young Scientists, Yerevan Armenia. Co-Chairmen
2010 First Armenian Anti Tobacco Congress “Smoking as Potential Risk Factor for Stroke” oral presentation, Yerevan, Armenia
2010 ENS Annual Joint Meeting, Berlin, Germany
2010 Neuropathic Pain Treatment: Launch of Qutenza. Meeting in Tbilisi, Georgia
2011 Neurological Depression, Yerevan, Armenia
2011 V International Conference on Modern Aspects of Rehabilitation in Medicine, Yerevan, Armenia “Neuroprotection: A Modern Apporach”, oral presentation
2011 Dementia and Alzheimer Disease: Effective Diagnostics and Management, Yerevan, Armenia
2012 Stroke: Modern Approaches to Efficient Treatment, Yerevan, Armenia
2013 Neuropathic Pain: A Real Patient Beyond the Numbers and Advertisements, Yerevan, Armenia
2013 Mild Cognitive Impairment: How to Evaluate and Why to Treat Early, Yerevan, Armenia
The Chronological List of Selected Publications
1. Manvelyan H, Patrikyan D, Differential Treatment of IntracerebralHematoms of Various Ethiology, Materials of First Conference of the Armenian IBRO Association, Yerevan, 1996
2. Manvelyan H, Differential treatment of intracerebralhematoms (in Russian) Clinical Medicine Journal, Vol. 2, Yerevan, , 1997, 25-27
3. Patrikyan D, Khostikyan N, Fanardjian R, Manvelyan H,Pathohystological estimation of the meningo-capsular sutures application in the treatment of Chronic Subdural Hematoms (in Russian) Clinical Medicine Journal, Vol. 2, Yerevan,1997, 28-31
4. Fanardjian R, Manvelyan H, Martirossian H,Cerebral Hemodynamic Phases Following Severe Head Trauma:Hypoperfusion, Hyperemia and Vasospasm,Materials of Second Conference ofthe ArmenianIBROAssociation, Yerevan , 1998, 28
5. Fanardjian R, Manvelyan H, Peculiarities of Cerebral Blood Flow velocity after Traumatic Brain Injury (in Russian) Clinical Medicine Journal, Vol. 1# 6,Yerevan, 1998,24-25
6. Manvelyan H, Clinical-physiological investigation of Cerebral Blood Flow in Severe Head Injury (Review) (in Russian )Clinical Medicine Journal, Vo21, #9,Yerevan, 1999, 5-9
7. FanardjianR.V.,Gevorkian E.M, Manvelyan H (1999) Peculiarities of Cerebral Collateral Blood Circulation in Brain Ischemia Fifth IBRO World Congress of Neuroscience, Jerusalem, Israel, 155
8. Manvelyan H, Fanardjian R, TCD in SAH syndrome (in Russian) Clinical Medicine Journal, Vol. 21, #8 (15),Yerevan, 1999, 50-52
9. Patrikyan D, Manvelyan H, Treatment of the Bedsores in Patients with Spinal Cord Injury, Pan Asian Neurological II Congress Handbook, Lahore, Pakistan, 1999
10. Patrikyan D, Manvelyan H, Surgical treatment of bedsores in neurosurgical patients (in Russian) Clinical Medicine Journal, Vol.3, #9, Yerevan, 1999, 50-52
11. Manvelyan H, Fanardjian R, Patrikyan D, Quantitative Evaluation of Cerebral Blood Flow in Patients with Severe Head Injury Georgian Journal of Radiology, 2(5),Tbilisi, Georgia, 2000, 55-57
12. Fanardjian R,Manvelyan H,Cerebral Hemodynamics Monitoring in Severe Head Injury (in Russian) Medical University 70th anniversary Conference Textbook Yerevan,2000, 199-202
13. Manvelyan H, Fanardjian R,Dopplerographic Differentiation of the Stroke Third Conference of the Armenian IBRO Association, Yerevan, 2000, 22-23
14. Manvelyan H, Fanardjian R, Cerebral Blood Flow as a Predictor of Outcome Following Traumatic Brain Injury Modern Problems of Anesthesiology and Reanimatology, Materials of the 2nd Conference of Armenian Anesthesiologists and Reanimatologists, Yerevan, 2000, 148-149
15. Fanardjian R, Manvelyan H, Application of TranscranialDopplerography in Acute Stroke Modern Problems of Anesthesiology and Reanimatology, Materials of the 2nd Conference of Armenian Anesthesiologists and Reanimatologists, Yerevan, 2000, 188-189
16. Manvelyan H,Clinical–Physiological Investigation of Cerebral Blood Flow in Patients with Severe Traumatic Brain Injury (in Russian), Candidate (PhD) Dissertation Thesis, Yerevan, 2001
17. Manvelyan H, Some aspects of neurosurgical treatment of Dementia 12th World Congress of Neurosurgery, Sydney, Australia, 2001, 397 (P592)
18. Fanardjian R, Manvelyan H, Cerebral Blood Flow in Traumatic Brain Injury 12h World Congress of Neurosurgery, Sydney, Australia, 2001, 397 (P593)
19. SoghomonyanS.A.,Manvelyan H.M., Patrikyan D.A., Fanardjian R.V., Babayan P.H., Management of Anaesthesia during Neurosurgical Interventions in Patients with Eisenmenger`s Syndrome: Two Case Report (in Russian) Issues in Theoretical and Clinical medicine, Vol. 5, #1 (25), Yerevan, 2002, 56-59
20. Manvelyan H,Fanardjian R. Primary and Delayed Ischemia in Severe Traumatic Brain Injury, Journal of Neurotrauma, Vol. 19, Number 10, 2002,P517
21. PatrikyanD.A.,Fanardjian R.V., Manvelyan H.M.,Hystological Peculiarities of the Capsule Organization of Chronic Subdural Hematoms, (in Russian) Materials of 1st National Medical Conference ”Human Health”, Yerevan, Armenia, 2002, 117
22. Manvelyan H, Patrikyan D, Fanardjian R,The Problem of the Brain Death, (in Russian) Materials of 1st National Medical Conference ”Human Health”, Yerevan, 2002, 124
23. Manvelyan H, Patrikyan D, Fanardjian R, The Education of Medical Students to Neurosurgery, (in Russian), Materials of XVI Conference on Methodology and Research, Yerevan, Armenia, 2003,105
24. Manvelyan H,Fanardjian R, Arterial Vasospasm Following Traumatic and Spontaneous Subarachnoid Hemorrhage: Clinical Implications, Materials of Pan Armenian International Surgical Congress, # 7.2 Yerevan, 2003, 72
25. Manvelyan H, Fanardjian R, Patrikyan D,Neurosurgery Manual on Basics of Neurological Surgery for Medical Students, Yerevan, Armenia, 2004
26. Manvelyan H, C. Claus, B.S. Walker, S-E. Koh, W. Whetstone, L.J. Noble-Haeusslein, Age-Dependent Temporal Pattern of Cell Injury after Traumatic Brain Injury: Relation to Blood Flow and Activated Microglia/Macrophages, Journal of Neurotrauma, Vol. 22, # 10, 2005,P12
27. Claus CP, Koh SE, Walker BS, Whetstone W, Manvelyan H,Noble-Haeusslein LJ,Prolonged GR-1 Positive, Leukocytic Infiltration in the Injured Cortex is Age-Dependent andCorresponds to Lesion Volume Expansion,Journal of Neurotrauma,Vol. 22, # 10, 2005,P168
28. Yoneyama Т, Azari С, Manvelyan Н, Noble-HaeussleinLJ, Heme-Oxigenase-2 (HO-2) modulates Early Pathogenesis and Motor Recovery after Traumatic Brain Injury to the Immature Brain, Journal of Neurotrauma, Vol. 22, #10, 2005,P271
29. Potts MB, Koh SE, Whetstone WD, Walker BA, Yoneyama T, Claus CP, Manvelyan HM, Noble-Haeusslein LJ.Traumatic injury to the immature brain: inflammation, oxidative injury, and iron-mediated damageas potential therapeutic targets. NeuroRx. 2006 Apr;3(2):143-53
30. Manvelyan HM, Muradyan AA, Amirkhanyan YE, Karapetyan AA.Role of Non-Profit and Professionals Organizations in Health System Reorganizations in Armenia, Proceedings of 4th International Conference on Healthcare Systems, Slovakia, 2006: P6
31. Manvelyan HM, Iron as a New Therapeutic Target in Pediatric Neurotrauma, Vestnik IAELPS, Vol.11, N 8, 2006: 251-254
32. Manvelyan H, Apoptosis in Traumatic Brain InjuryVestnik IAELPS, Vol.11, N 8,2006: 247-251
33. Manvelyan H, Novel treatment methods in experimental pediatric traumatic brain injury (in Russian),Medical Science of Armenia, Vol. XLVII, issue 2, 2006, 240-249
34. Manvelyan H, Cerebral Blood Flow in Experimental NeurotraumaMedical Science of Armenia, Vol. XLVII, issue 2, 2006, 221-235
35. Manvelyan HM, Temporal patterns of Irreversibly Injured Cells, Activated Microglia/Macrophages and Cerebral Blood Flow in Neurotrauma. Abstract Book of 2nd International Conference of the National Neuroscience Society of Romania, Bucharest 2006, Romania, P20
36. Manvelyan HM,Karapetyan AA, Grigoryan GV. The Comprehensive Appreciation of the Role of Microglia as Central Nervous System’s Innate Immune System in Acute and Chronic Neuroinflammation, Vestnik IAELPS, Vol.11, N 8, 2nd issue 2006, 228-232
37. Manvelyan HM, Features of Immune Inflammation in Traumatic Brain Injury (in Russian), Vestnik IAELPS, Vol.11, N 8, 2nd issue 2006, 182-187
38. ManvelyanHM, ZilfyanAV. LaboratorydetectionofApoptosisbytheTUNEL (TdT-FragEL* DNA Fragmentation detection)imuno-hystochemical method. Materials of Medical Diagnostics 1st Delta Conference,2006,Yerevan, Armenia, 84-87
39. Manvelyan HM. Contemporary experimental models of traumatic brain injury. Georgian Medical News, 2006, Georgia, No 11 (140), 13-16
40. Manvelyan HM. Cortical perfusion is an important factor, but not a determinant of increased vulnerability of immature to traumatic brain injury. Georgian Medical News, 2006, Georgia, No 12 (141), 24-28
41. Manvelyan HM. The role of regional immune, morphological and metabolic shifts in pathogenesis of experimental cortical injury. (Doctoral (DSci) Thesis), Yerevan, Armenia, 2007
42. Manvelyan HM, Gevorgyan EM. The early detection framework and database of Alzheimer’s disease in Armenia. Alzheimer and Dementia, 2007, P117, Volume 3 , Issue 3 , Pages S136 – S136
43. Manvelyan HM, Karapetyan AA, Gevorgyan GV. Efficacy of FlourescentLectin Studies in the Brain Research. Materials of Yerevan State Medical University Scientific Conference, Yerevan, Armenia, 2007, 97-98
44. Manvelyan HM, Muradyan HM, Grigoryan GV. Efficacy of CT scans of the brain in early diagnostics of Dementia. Modern problems of fundamental and clinical medicine. Proceedings of 8thConfernece of Young Medics of NIS. Almaty, Kazakhistan, 2007, 154-156
45. Manvelyan HM, Hambardzumyan HD. Comprehensive Approach to Evaluation and Treatment of Patients with Discirculatory Encephalopathy Vestnik IAELPS, Vol.13, N 1,2008, 224-228
46. Manvelyan HM, Karapetyan AA, Karapetyan AH, Gevorgyan EM. Efficacy of α-blockers in treatment of vascular dementia (article is in Russian), Russian Medical Journal, Moscow, Russia#8 (312), 2008,53-58
47. Manvelyan HM, Khachatryan SG. The Quality of Life in Patients with Epilepsy. Clinical Medicine Journal,Vol.41, #6,Yerevan, 2008, 44-61
48. Manvelyan HM, Hakobyan ME, Angelova IB. Epidemiology of Multiple Sclerosis in Armenia: Threatening Growth. The New Armenian Medical Journal,Vol.3, 2008, 24-33
49. Manvelyan HM.Unveiling brain innate immune system: the role of microglia.Neurochemical Research, 2008,v.33, No. 6, 1150-1167
50. Manvelyan HM, Khachatryan SG. Depression in Epilepsy, MedicinskiVestnikErebouni, 1 (33), 2008, 39-57
51. Manvelyan HM, Muradyan HM. CT and MRI in Dementive Diseases of the Brain, Innovative approaches in Radiological Diagnostics. Yerevan, 2008, 65-67
52. Manvelyan HM, Khachatryan SG. Prevalence of depression in patients with epilepsy and comparison with chronic somatic disorders in Armenia (a pilot sudy). European Journal of Neurology,Vol.15, Suppl. 3, Aug 2008, P1218, 89
53. Manvelyan HM, Hambardzumyan HD, Karapetyan AA, Gevorgyan EM. Dementia in Armenia: Vascular vs. Alzheimer Disease. European Journal of Neurology,Vol.15, Suppl. 3, Aug 2008, P2059, 235
54. Manvelyan HM, Hakobyan ME, Angelova IB, Khachatryan SG. Epidemiology of MS in Armenia: threatening growth rates. European Journal of Neurology,Vol.15, Suppl. 3, Aug 2008, P2653, 368
55. H.M. Manvelyan, S.G. Khachatryan, Z.D. Tavadyan, N.S. Yeghiazaryan, G.R. Melikyan, T.H. Stepanyan, Quantitative assessment of quality of life ratings in Armenian Epilepsy patients. Issues of theoretical and clinical medicine, 2008; issue 11, 2(50); 14-20, Yerevan.
56. Manvelyan HM, Gevorgyan EM, Aghajanov MI, Karapetyan AG. Alzheimer Disease and Relative Dementia Disorders in Armenia Dementia in the Middle East 5th Regional Conference 2009, Limassol, Cyprus
57. Manvelyan HM, Hambardzumyan HD. The Problem of Effective Treatment of Post Stroke Dementia Issues in Theoretical and Clinical medicine, Vol. 12, #2 (54), Yerevan, 2009, 29-32P2096
58. H.M. Manvelyan, A.A. Karapetyan, H.D. Hambardzumyan,A.H. Karapetyan, M.E. Hakobyan, E.M. Gevorgyan,M.I. Aghajanov. Toward solving the problem of Alzheimer and related dementias in Armenia: preliminary results. European Journal of Neurology Volume 16, Supplement 3, September 2009 P2096
59. H. Manvelyan,S. Khachatryan. Health-related quality of life in patientswith epilepsy and comparison withchronic somatic disorders. P2427European Journal of Neurology Volume 16, Supplement 3, September 2009
60. H.M. Manvelyan,H.D. Hambardzumyan, A.A. Karapetyan,A.H. Karapetyan, E.M. Gevorgyan Parkinson’s disease and relatedsyndromes in Armenia: diagnostic andevaluation gaps, P2648European Journal of Neurology Volume 16, Supplement 3, September 2009
61. Aghajanov M, Vahradyan H and Manvelyan H. Dementia is an Actual Problem. Aroghchapahutyun(Health) Armeian Monthly Journal, No 2 (283), 2009, p 9-10
62. Manvelyan H.M, The Pathogenic Role Of Age-Dependent Temporal Patterns Of Local Blood Perfusion, Activated Microglia/Macrophages, Apoptosis And Free Iron Accumulation In Experimental Neurotrauma, The New Armenian Medical Journal, Vol. 3, No. 4, p. 4-17
63. Yoneyama-Sarnecky T, Manvelyan HM, Olivas AD, Azari S, Ferriero DM, Noble-Haeusslein LJ. Heme Oxygenase-2 Modulates Early Pathogenesis after Traumatic Injury to the Immature Brain. Developmental Neuroscience 2010;32:81–90 DOI: 10.1159/000258700
64. Manvelyan HM, Khachiyan VE. Low Back Pain: The Role of the History and Neurologic Examination in Accurate Diagnosis (Literature Review) MedicinskiVestnikErebouni, #1 (41), 2010, pp 6-20
65. Manvelyan HM, Hambardzumyan HD. Dynamic Evaluation of Cognitive Disorders in Chronic Vascular Encephalopathies with Modified Wechsler Scale. MedicinskiVestnikErebouni, #1 (41), 2010, pp 74-78
66. Manvelyan H, Avetisyan A, Sargsyan R. Cognitive Disorders in Armenia: Types of Dementia. Materials of International Congress of Young Scientists. The New Armenian Medical Journal. Vol.4, No 1, 2010 26-27
67. Manvelyan H, Kalayjyan V. Patent Foramen Ovale (PFO) as a Possible Risk Factor for Ischemic Stroke in a Young Patient: Case Report Materials of International Congress of Young Scientists. The New Armenian Medical Journal, 2010. 65-66
68. Manvelyan H, Sargsyan R, Avetisyan A, Aleksanyan A. Dementia Evaluation Efficacy and Sensitivity by Different Scales Materials of International Congress of Young Scientists. The New Armenian Medical Journal 2010. 124-125
69. Manvelyan H, Vekilyan A, Karapetyan A, Gevorgyan E. Concerning Prevalence of Migraine in Different Regions of Armenia. Materials of International Congress of Young Scientists. The New Armenian Medical Journal 2010. 144-145
70. Manvelyan H, Yong Scientist Coucul – Model For Transition To MdPhd Combine Program In Yerevan State Medical University, ORPHEUS, 5th European Congress, Vienna, Austria, P21
71. Manvelyan H, Yaghjyan G and Muradyan A, Phd In Post-Soviet Country: A Challenge, ORPHEUS, 5th European Congress, Vienna, Austria, P20
72. H. Manvelyan, A. Avetisyan, R. Sargsyan, Clinical structure of dementia syndromein Armenia, 2010 EFNS,European Journal of Neurology 17 (Suppl. 3), 351–625 P2047, p370, P2047
73. H.M. Manvelyan, H.D. Hambardzumyan, A.A. Karapetyan,E.M. Gevorgyan. The rate of transformation of mild cognitive impairment (MCI) into mild/moderate dementia, 2010 EFNS European Journal of Neurology 17(Suppl. 3), 72–350, p91, P1041
74. H. Manvelyan, A. Karapetyan, M. Hakobyan, A. Nazaryan,E. Gevorgyan The role of emotional instability andstress in onset of multiple sclerosis. 2010 EFNS European Journal of Neurology 17(Suppl. 3), 72–350, P1419, p 237
75. H.M. Manvelayn, H.R. Vekilyan, A.H. Karapetyan, E.M. Gevorgyan,Epidemiology of headaches in Armenia:preliminary results of a multicenter study. 2010 EFNS European Journal of Neurology 17 (Suppl. 3), 72–350, p257, P1462
76. Manvelyan H, Avetisyan A, Karapetyan A, Karapetyan A, Vekilyan H, Gevorgyan E. Primary Headaches in Multiple Sclerosis: Co morbidity or Symptom? The Journal of Headache and Pain, Vol 11, Suppl. 1, 2nd EHMTIC Proceedings, Nice, 2010, 361
77. Manvelyan H.M., H.R. Vekilyan, A.H. Karapetyan, E.M. Gevorgyan. The epidemiology of migraine in Armenia: preliminary results of simultaneous multicenter study. The Journal of Headache and Pain, Vol 11, Suppl. , 2nd EHMTIC Proceedings, Nice, 2010, 139
78. ManvelyanHM, Olivas AD, Azari S, Ferriero DM, Noble-Haeusslein LJ. Heme Oxygenase-2 Modulates Early Pathogenesis after Traumatic Injury to the Immature Brain. Developmental Neuroscience 2010;32:81–90 DOI: 10.1159/000258700
79. Manvelyan H.M, Avetisyan A., M. Hakobyan, A. Karapetyan, A. Karapetyan, E. Gevorkyan, Cognitive Impairment Vs. Depression In Patients With Parkinson Disease/ Syndrome, Journal of the Neurological Science, Proceedings of 7th International Congress on Mental Dysfunctions and Other Non-Motor features in Parkinson`s Disease and Related Disorders. Barcelona, SpainVolume 310, Issues 1-2, Pages 1-290
80. Claus CP, Tsuru-Aoyagi K, Adwanikar H, Walker B, Manvelyan H, Whetstone W, Noble-Haeusslein LJ. Age is a determinant of leukocyte infiltration and loss of cortical volume after traumatic brain injury.Dev Neurosci. 2010;32(5-6):454-65. Epub 2010 Sep 15. Erratum in: Dev Neurosci. 2010;32(5-6):465. PMID: 20847543
81. Hakobyan ME, Nazaryan AV, Santrosyan NM and Manvelyan HM. Indexes of Disease Duration, Speed of Progression and Relapses Indexes of Patients with Multiple Sclerosis. Issues in Theoretical and Clinical Medicine (Armenia), Vol 14, No 4(64), 2011, p. 57-8
82. Avagyan G, Khachatryan E, Sahakyan A, Sargsyan R, Koshtoyan H, Eghoyan K, Khachatryan L, Aleksanyan A, Avetisyan A, Karapetyan A and Manvelyan H. Lyme Disease: A New Healthcare Issue in Armenia. Medicine, Science and Education (Armenia), No.8, 2011, p.16-22
83. Avetisyan A, Hakobyan M, Karapetyan A, Manvelyan H. New Health Concern in Armenia: Lyme Disease, Omitted with Multiple Sclerosis (ID:147). Proceedings of 3rd International Medical Congress of Armenia, Yerevan Armenia, 2011
84. Sahakyan A, Podosyan H, Khachatryan L, Harutyunyan K, Eganyan S, Koshtoyan H, Eghoyan K, Baghdasaryan Z, Sargsyan R, Karapetyan AH, Karapetyan AA, Gevorgyan E and Manvelyan H. Hashimoto Autoimmune Thyroiditis With Primary Neurological Manifestations (ID: 556). Proceedings of 3rd International Medical Congress of Armenia, Yerevan Armenia, 2011
85. Kaladjyan V, Manvelyan H. Application of the Thrombolytic Therapy in Acute Stage of Ischemic Stroke (ID: 602). Proceedings of 3rd International Medical Congress of Armenia, Yerevan Armenia, 2011
86. Manvelyan HM. What is Neuropathic Pain? Pharma (Armenia), No1, 2011, p.110-111
87. Manvelyan HM, Karapetyan AA, Avetisyan AY, Hambardzumyan HD, Karapetyan AH, Aghajanov MI. Dementia and Depression: Two Existing Co-morbidities. (P1-159). Alzheimer and Dementia Journal, Abstracts of the Alzheimer`s Association International Conference, 2011, Vol. 7, Issue 4, Suppl. 1,p162
88. H.D. Hambardzumyan, H.S. Podosyan, A.B. Karapetyan, A.V. Nazaryan, A.V. Stepanyan, E.S. Khachatryan and H.M. Manvelyan. Clinical Distribution of Dementia Syndrome in Armenia: Results of 3 Years Long Study,XXth World Congress of Neurology, Abstract Book, Marrakesh, Morocco, 2011, p 884
89. A.Y.Avetisyan, A.Y. Sahakyan, M.E. Hakobyan, E.M. Gevorgyan and H.M. Manvelyan. Demyelinating Disease and Multiple Sclerosis in Armenia: An Emerging Problem. XXth World Congress of Neurology, Abstract Book, Marrakesh, Morocco, 2011, p 966
90. AvagyanG.A.,Khachatryan E.A., Sahakyan A.E., Sargsyan R.T., Koshtoyan H.H., Eghoyan K.N., Khachatryan L.R., Aleksanyan A.M., Avetisyan A.E., Karapetyan A.H., Manvelyan H.M. Lyme Disease: A new healthcare issue in Armenia. The New Armenian Medical Journal (ISSN 1820-0254), 2012, September, Vol. 6, No 3, pages 60-66
91. A. Avetisyan, G. Avagyan, A.Sahakyan, H. Manvelyan. Multiple Sclerosis in Armenia. Quality of life and depression. XXIth World Congress of Neurology (WCN 2013), No2766, Topic: 6-MS &Demyelinating Diseases, Vienna, Austria, Journal of the Neurological Sciences 333 (2013)
92. A.Sahakyan, G. Avagyan, A. Avetisyan, H. Manvelyan. Duration of MS on Quality of Life: Preliminary results of Armenian study. XXIst World Congress of Neurology (WCN 2013), No2849, Topic: 6-MS &Demyelinating Diseases, Vienna, Austria, Journal of the Neurological Sciences 333 (2013)
93. I. Gabrielyan, A. Zakaryan, H. Manvelyan, Assessment of functional outcome and quality of life after aneurysmal subarachnoid hemorrhage, XXIst World Congress of Neurology (WCN 2013), p 256, Journal of the Neurological Sciences 333 (2013)
94. G. Avagyan, A. Sahakyan, A. Avetisyan, H. Manvelyan. Disability Assessment Results of MS Patients in Armenia. XXIst World Congress of Neurology (WCN 2013), No2840, Journal of the Neurological Sciences 333 (2013)
95. H.R. Vekilyan, A.H. Karapetyan, E.M. Gevorkyan,H.M. Manvelyan, Cluster headaches: Underestimated medical problem in Armenia, XXIst World Congress of Neurology (WCN 2013), No2840, Journal of the Neurological Sciences 333 (2013)
96. AvetisyanA.E.,Avagyan G.A., Sahakyan A.E., Avetisyan G.A., Manvelyan H.M., CONTEMPORARY DIAGNOSTIC CRITERIA OF MULTIPLE SCLEROSIS. Scientific Journal of Medicine, Science and Education. ISSN 1829-1775, pages 31-41 (article is in Armenian), Yerevan, Armenia
97. A.A. Karapetyan, H. Manvelyan, Fibromyalgia: Another clinical feature of generalized pain syndrome? No 1735, p e526, XXIst World Congress of Neurology (WCN 2013), No2840, Journal of the Neurological Sciences 333 (2013)
98. H. Hakobyan, H. Manvelyan.The burden of paediatric cerebral palsy on caregiver’s mental health, No 2830, p e545, XXIst World Congress of Neurology (WCN 2013), No2840, Journal of the Neurological Sciences 333 (2013)
99. A. Avetisyan, K. Harutyunyan, A. Voskanyan, I. Gabrielyan, A. Karapetyan, E. Gevorgyan, H. Manvelyan. CASE REPORT ON WILSON’S DISEASE:HOW FAR THE WRONG DIAGNOSIS COULD GO? XX World Congress on Parkinson’s Disease and Related Disorders, Geneva, Switzerland (in press)
100. K. Harutyunyan, I. Gabrielyan, A. Voskanyan, H. Amirjanyan, L. Khachatryan, A. Avetisyan, A. Sahakyan, G. Avagyan, A. Karapetyan and H. Manvelyan. THE PROBLEM OF DIAGNOSTICS AND MANAGEMENT OF PROGRESSIVE SUPRANUCLEAR PALSY IN ARMENIA. XX World Congress on Parkinson’s Disease and Related Disorders, Geneva, Switzerland (in press)
101. A. Voskanyan, K. Harutyunyan, I. Gabrielyan, A. Avetisyan, H. Amirjanyan, L. Khachatryan, G. Avagyan, A. Sahakyan, A. Karapetyan and H. Manvelyan. CASE OF FAMILIAL OPCA. World Congress on Parkinson’s Disease and Related Disorders, Geneva, Switzerland (in press)
102. I. Gabrielyan, K. Harutyunyan, A. Voskanyan, A. Avetisyan, G. Avagyan, A. Sahakyan, H. Hambardzumyan, A. Karapetyan and H. Manvelyan. COMBINATION OF PARKINSONISM, DEMENTIA AND MOTOR NEURON DISEASE: FOUR CASES OF GUAM SYNDROME IN ARMENIA? World Congress on Parkinson’s Disease and Related Disorders, Geneva, Switzerland (in press)